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全自动集装箱码头装卸系统集成了当今世界各项先进技术,在研发、制造、调试过程中,都要坚持质量第一、安全第一的原则,确保各项技术参数可靠,设备运行稳定。在总结国内几个全自动码头装卸系统的质量管理方法与经验的基础上,结合自动化码头自身特点,给出全自动集装箱码头装卸系统主要质量管理方法,进一步丰富发展自动化码头装卸系统建造过程中的“不欠债离岸”质量管理理念。 相似文献
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Hiroyuki Koide Satoshi Hirano Takafumi Ide Kazuhiro Saito Hikaru Suzuki Go Yasuno Yoshitaka Hamashima Sei Yonezawa Naoto Oku Tomohiro Asai 《Advanced functional materials》2021,31(3):2005641
Protein affinity reagents (e.g., antibodies) are often used for basic research, diagnostics, separations, and disease therapy. Although a lot of “synthetic” protein affinity reagents have been developed as a cost-effective alternative to antibodies, their low biocompatibility is a considerable problem for clinical application. Lipid nanoparticles (LNP) represent a highly biocompatible drug delivery agent. However, little has been reported that LNP itself works as a protein affinity reagent in living animals. Here, LNP is engineered for binding to and neutralizing a target toxic peptide in living animals by multifunctionalization with amino acid derivatives. Multifunctionalized LNP (MF-LNP) is prepared using amino acid derivative-conjugated lipids. Optimized MF-LNP exhibits nanomolar affinity to the target toxic peptide and inhibits toxic peptide-dependent hemolysis and cytotoxicity. In addition, MF-LNP captures and neutralizes the toxic peptide after intravenous injection in the bloodstream; in addition, MF-LNP does not release the toxic peptide in the accumulated organ. These results reveal the potential of using LNP as a highly biocompatible protein affinity reagent such as an antidote. 相似文献
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Resilient cows are minimally affected in their functioning by infections and other disturbances, and recover quickly. Herd management is expected to have an effect on disturbances and the resilience of cows, and this effect was investigated in this study. Two resilience indicators were first recorded on individual cows. The effect of herd-year on these resilience indicators was then estimated and corrected for genetic and year-season effects. The 2 resilience indicators were the variance and the lag-1 autocorrelation of daily milk yield deviations from an expected lactation curve. Low variance and autocorrelation indicate that a cow does not fluctuate much around her expected milk yield and is, thus, subject to few disturbances, or little affected by disturbances (resilient). The herd-year estimates of the resilience indicators were estimated for 9,917 herd-year classes based on records of 227,655 primiparous cows from 2,644 herds. The herd-year estimates of the resilience indicators were then related to herd performance variables. Large differences in the herd-year estimates of the 2 resilience indicators (variance and autocorrelation) were observed between herd-years, indicating an effect of management on these traits. Furthermore, herd-year classes with a high variance tended to have a high proportion of cows with a rumen acidosis indication (r = 0.31), high SCS (r = 0.19), low fat content (r = ?0.18), long calving interval (r = 0.14), low survival to second lactation (r = ?0.13), large herd size (r = 0.12), low lactose content (r = ?0.12), and high production (r = 0.10). These correlations support that herds with high variance are not resilient. The correlation between the variance and the proportion of cows with a rumen acidosis indication suggests that feed management may have an important effect on the variance. Herd-year classes with a high autocorrelation tended to have a high proportion of cows with a ketosis indication (r = 0.14) and a high production (r = 0.13), but a low somatic cell score (r = ?0.17) and a low proportion of cows with a rumen acidosis indication (r = ?0.12). These correlations suggest that high autocorrelation at herd level indicates either good or poor resilience, and is thus a poor resilience indicator. However, the combination of a high variance and a high autocorrelation is expected to indicate many fluctuations with slow recovery. In conclusion, herd management, in particular feed management, seems to affect herd resilience. 相似文献
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在传统静态表情识别研究基础上,提出一种简单的人脸裁剪方法,再用浅层卷积神经网络进一步提取特征并进行表情识别。以CK+和JAFFE为实验数据集,进行预处理效果对比实验、数据增强实验、单种表情识别实验和跨数据集六分类实验。结果表明,针对数据量较少的情况,提出的表情识别方法效果明显且鲁棒性更优。 相似文献
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在烟气制酸,废酸废水处理系统工序中,pH 电极的在线应用较为广泛。为了满足工艺条件的需求 ,经常会对 pH 值进行连续在线监测及控制。由于生产现场的特殊工况 , 电极的检测球泡浸在被测溶液中,经常会发生结垢的现象 ;导致测量数据的失真或无法获取检测值 , 这种现象是电极使用中的常见现象同时也是 PH 电极在实际使用中的瓶颈问题。本文针对电极检测中出现的问题进行了详尽的分析、论证、汇总,提出了相应的解决办法及改进优化措施。 相似文献